Malate-aspartate shuttle

AST ( GOT ) participates in malate-aspartate shuttle.
Malate-aspartate shuttle is necessary for oxaloacetate transportation form mitochondrial matrix to cytosol.
Pyruvate, lactate, and amino acid ( ex. alanin ) are used for gluconeogenesis.
But, note that fatty acids are not used for gluconeogenesis.
<SEE Mitochondria>
<RETURN to AST(GOT)>
<RETURN to INDEX>
Key Words :
Acyl-CoA, α-ketoglutarate, Alanin, Aspartate, β-oxidation cycle,
Citrate, Citrate sunthase, Fatty acids,
GDH, Gluconeogenesis, Glucose, Glutamate, Glycolysis, Glutamate-aspartate transporter,
Kreb's citric acid cycle, Lactate, LDH,
Malate, Malate-α-ketoglutarate transporter, Malate-aspartate shuttle, MDH,
NAD+, NADH2+,
Oxaloacetate, PEPCK, Phosphoenolpyruvate,
Pyruvate, Pyruvate carboxylase, Pyruvate dehydrogenase, Pyruvate kinase,
ALT(GPT), m-AST (m-AST), s-AST (s-GOT),